Cargando…

Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery

INTRODUCTION: We present the case of a patient with dilatative cardiomyopathy waiting for heart transplantation with pleural effusion to be subjected to pleural biopsy, treated with preoperative infusion of levosimendan to improve heart performances. PRESENTATION OF CASE: A 56-year-old man (BMI 22,4...

Descripción completa

Detalles Bibliográficos
Autores principales: Nespoli, Moana Rossella, Rispoli, Marco, Mattiacci, Dario Maria, Esposito, Marianna, Corcione, Antonio, Curcio, Carlo, Buono, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983642/
https://www.ncbi.nlm.nih.gov/pubmed/27518430
http://dx.doi.org/10.1016/j.ijscr.2016.08.003
_version_ 1782447929461571584
author Nespoli, Moana Rossella
Rispoli, Marco
Mattiacci, Dario Maria
Esposito, Marianna
Corcione, Antonio
Curcio, Carlo
Buono, Salvatore
author_facet Nespoli, Moana Rossella
Rispoli, Marco
Mattiacci, Dario Maria
Esposito, Marianna
Corcione, Antonio
Curcio, Carlo
Buono, Salvatore
author_sort Nespoli, Moana Rossella
collection PubMed
description INTRODUCTION: We present the case of a patient with dilatative cardiomyopathy waiting for heart transplantation with pleural effusion to be subjected to pleural biopsy, treated with preoperative infusion of levosimendan to improve heart performances. PRESENTATION OF CASE: A 56-year-old man (BMI 22,49) with dilatative cardiomyopathy (EF 18%) presented right pleural effusion. The levosimendan treatment protocol consisted of 24 h continuous infusion (0,1 ug/kg/min), without bolus. The patient was under continuous hemodynamic monitoring prior, during and after levosimendan administration. The surgery for pleural biopsy was performed with uniportal Video Assisted Thoracoscopic approach (VATS). DISCUSSION: A significant increase of Cardiac Index (CI) and Stroke Volume Index (SVI) were observed at 4 h after infusion initiation and was sustained during the next 24 h after the end of infusion. Levosimendan administration was safe. CONCLUSION: In this case the prophylactic preoperative levosimendan administration is safe and effective in cardiac failure patient undergoing thoracic surgery, but prophylactic preoperative levosimendan treatment in these patients merits further study.
format Online
Article
Text
id pubmed-4983642
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-49836422016-08-22 Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery Nespoli, Moana Rossella Rispoli, Marco Mattiacci, Dario Maria Esposito, Marianna Corcione, Antonio Curcio, Carlo Buono, Salvatore Int J Surg Case Rep Case Report INTRODUCTION: We present the case of a patient with dilatative cardiomyopathy waiting for heart transplantation with pleural effusion to be subjected to pleural biopsy, treated with preoperative infusion of levosimendan to improve heart performances. PRESENTATION OF CASE: A 56-year-old man (BMI 22,49) with dilatative cardiomyopathy (EF 18%) presented right pleural effusion. The levosimendan treatment protocol consisted of 24 h continuous infusion (0,1 ug/kg/min), without bolus. The patient was under continuous hemodynamic monitoring prior, during and after levosimendan administration. The surgery for pleural biopsy was performed with uniportal Video Assisted Thoracoscopic approach (VATS). DISCUSSION: A significant increase of Cardiac Index (CI) and Stroke Volume Index (SVI) were observed at 4 h after infusion initiation and was sustained during the next 24 h after the end of infusion. Levosimendan administration was safe. CONCLUSION: In this case the prophylactic preoperative levosimendan administration is safe and effective in cardiac failure patient undergoing thoracic surgery, but prophylactic preoperative levosimendan treatment in these patients merits further study. Elsevier 2016-08-04 /pmc/articles/PMC4983642/ /pubmed/27518430 http://dx.doi.org/10.1016/j.ijscr.2016.08.003 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nespoli, Moana Rossella
Rispoli, Marco
Mattiacci, Dario Maria
Esposito, Marianna
Corcione, Antonio
Curcio, Carlo
Buono, Salvatore
Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
title Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
title_full Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
title_fullStr Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
title_full_unstemmed Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
title_short Preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
title_sort preoperative optimization with levosimendan in heart failure patient undergoing thoracic surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983642/
https://www.ncbi.nlm.nih.gov/pubmed/27518430
http://dx.doi.org/10.1016/j.ijscr.2016.08.003
work_keys_str_mv AT nespolimoanarossella preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery
AT rispolimarco preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery
AT mattiaccidariomaria preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery
AT espositomarianna preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery
AT corcioneantonio preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery
AT curciocarlo preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery
AT buonosalvatore preoperativeoptimizationwithlevosimendaninheartfailurepatientundergoingthoracicsurgery