Cargando…

A Small Aptamer with Strong and Specific Recognition of the Triphosphate of ATP

[Image: see text] We report the in vitro selection of an RNA-based ATP aptamer with the ability to discriminate between adenosine ligands based on their 5‘ phosphorylation state. Previous selection of ATP aptamers yielded molecules that do not significantly discriminate between ligands at the 5‘ pos...

Descripción completa

Detalles Bibliográficos
Autores principales: Sazani, Peter L., Larralde, Rosa, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2004
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983724/
https://www.ncbi.nlm.nih.gov/pubmed/15237981
http://dx.doi.org/10.1021/ja049171k