Hepatitis B virus X protein mediated suppression of miRNA-122 expression enhances hepatoblastoma cell proliferation through cyclin G1-p53 axis

BACKGROUND: Hepatitis B virus (HBV) X protein (HBx) reported to be associated with pathogenesis of hepatocellular carcinoma (HCC) and miR-122 expression is down regulated in HCC. Previous studies reported miR-122 targets cyclin G1 (CCNG1) expression and this in turn abolishes p53-mediated inhibition...

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Detalles Bibliográficos
Autores principales: Bandopadhyay, Manikankana, Sarkar, Neelakshi, Datta, Sibnarayan, Das, Dipanwita, Pal, Ananya, Panigrahi, Rajesh, Banerjee, Arup, Panda, Chinmay K., Das, Chandrima, Chakrabarti, Shekhar, Chakravarty, Runu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983788/
https://www.ncbi.nlm.nih.gov/pubmed/27528885
http://dx.doi.org/10.1186/s13027-016-0085-6

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