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Pichia pastoris Exhibits High Viability and a Low Maintenance Energy Requirement at Near-Zero Specific Growth Rates
The yeast Pichia pastoris is a widely used host for recombinant protein production. Understanding its physiology at extremely low growth rates is a first step in the direction of decoupling product formation from cellular growth and therefore of biotechnological relevance. Retentostat cultivation is...
Autores principales: | Rebnegger, Corinna, Vos, Tim, Graf, Alexandra B., Valli, Minoska, Pronk, Jack T., Daran-Lapujade, Pascale, Mattanovich, Diethard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984280/ https://www.ncbi.nlm.nih.gov/pubmed/27208115 http://dx.doi.org/10.1128/AEM.00638-16 |
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