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Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review

We report the 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) findings of sclerosing angiomatoid nodular transformation (SANT) of the spleen. The patient was a 37-year-old woman with a splenic mass incidentally found on abdominal ultrasound. FDG-PET/CT showed...

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Autores principales: Imamura, Yumi, Nakajima, Reiko, Hatta, Kazuha, Seshimo, Akiyoshi, Sawada, Tatsuo, Abe, Koichiro, Sakai, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984319/
https://www.ncbi.nlm.nih.gov/pubmed/27570634
http://dx.doi.org/10.1177/2058460116649799
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author Imamura, Yumi
Nakajima, Reiko
Hatta, Kazuha
Seshimo, Akiyoshi
Sawada, Tatsuo
Abe, Koichiro
Sakai, Shuji
author_facet Imamura, Yumi
Nakajima, Reiko
Hatta, Kazuha
Seshimo, Akiyoshi
Sawada, Tatsuo
Abe, Koichiro
Sakai, Shuji
author_sort Imamura, Yumi
collection PubMed
description We report the 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) findings of sclerosing angiomatoid nodular transformation (SANT) of the spleen. The patient was a 37-year-old woman with a splenic mass incidentally found on abdominal ultrasound. FDG-PET/CT showed weak FDG accumulation (maximum standardized uptake value = 3.65). An unenhanced CT scan showed a low density and well-circumscribed splenic tumor that demonstrated weak enhancement from the arterial to delayed phase. Although hemangioma or hamartoma of the spleen was preoperatively diagnosed, histopathological examination revealed SANT. Therefore, when a splenic tumor with weak contrast medium enhancement and low FDG accumulation is observed, SANT should be considered as a differential diagnosis. Although CT and magnetic resonance imaging features of SANT have been reported, there are few reports on FDG-PET/CT findings. We report the radiological features of SANT, including FDG-PET/CT, and review the literature on SANT.
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spelling pubmed-49843192016-08-26 Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review Imamura, Yumi Nakajima, Reiko Hatta, Kazuha Seshimo, Akiyoshi Sawada, Tatsuo Abe, Koichiro Sakai, Shuji Acta Radiol Open Case Report We report the 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) findings of sclerosing angiomatoid nodular transformation (SANT) of the spleen. The patient was a 37-year-old woman with a splenic mass incidentally found on abdominal ultrasound. FDG-PET/CT showed weak FDG accumulation (maximum standardized uptake value = 3.65). An unenhanced CT scan showed a low density and well-circumscribed splenic tumor that demonstrated weak enhancement from the arterial to delayed phase. Although hemangioma or hamartoma of the spleen was preoperatively diagnosed, histopathological examination revealed SANT. Therefore, when a splenic tumor with weak contrast medium enhancement and low FDG accumulation is observed, SANT should be considered as a differential diagnosis. Although CT and magnetic resonance imaging features of SANT have been reported, there are few reports on FDG-PET/CT findings. We report the radiological features of SANT, including FDG-PET/CT, and review the literature on SANT. SAGE Publications 2016-08-10 /pmc/articles/PMC4984319/ /pubmed/27570634 http://dx.doi.org/10.1177/2058460116649799 Text en © The Foundation Acta Radiologica 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Imamura, Yumi
Nakajima, Reiko
Hatta, Kazuha
Seshimo, Akiyoshi
Sawada, Tatsuo
Abe, Koichiro
Sakai, Shuji
Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review
title Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review
title_full Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review
title_fullStr Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review
title_full_unstemmed Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review
title_short Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review
title_sort sclerosing angiomatoid nodular transformation (sant) of the spleen: a case report with fdg-pet findings and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984319/
https://www.ncbi.nlm.nih.gov/pubmed/27570634
http://dx.doi.org/10.1177/2058460116649799
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