Cargando…

Anti‐flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues

A series of tritylated and dimethoxytritylated analogues of selected pyrimidine and purine nucleosides were synthesized and evaluated for their in vitro inhibitory activity against two important members of the genus Flavivirus in the Flaviviridae family, the yellow fever (YFV) and dengue viruses (DE...

Descripción completa

Detalles Bibliográficos
Autores principales:	McGuigan, Christopher, Serpi, Michaela, Slusarczyk, Magdalena, Ferrari, Valentina, Pertusati, Fabrizio, Meneghesso, Silvia, Derudas, Marco, Farleigh, Laura, Zanetta, Paola, Bugert, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984408/ https://www.ncbi.nlm.nih.gov/pubmed/27551659 http://dx.doi.org/10.1002/open.201500216

Ejemplares similares

Chemoselective N-Deacetylation of Protected Nucleosides and Nucleotides Promoted by Schwartz's Reagent
por: Ferrari, Valentina, et al.
Publicado: (2015)

Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides
por: McGuigan, Christopher, et al.
Publicado: (2013)

Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2′‐Deoxypseudoisocytidine
por: Serpi, Michaela, et al.
Publicado: (2017)

Phosphoramidates and phosphonamidates (ProTides) with antiviral activity
por: Slusarczyk, Magdalena, et al.
Publicado: (2018)

Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives
por: Hasaneen, Noha, et al.
Publicado: (2019)

Synthesis and biological evaluation of phosphoramidate prodrugs of two analogues of 2-deoxy-d-ribose-1-phosphate directed to the discovery of two carbasugars as new potential anti-HIV leads
por: Hamon, Nadège, et al.
Publicado: (2015)

Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs
por: Pileggi, Elisa, et al.
Publicado: (2018)

Modification of Purine and Pyrimidine Nucleosides by Direct C-H Bond Activation
por: Liang, Yong, et al.
Publicado: (2015)

Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides
por: Rao, Jagadeeshwar R., et al.
Publicado: (2007)

Analogues of Pyrimidine Nucleosides as Mycobacteria Growth Inhibitors
por: Alexandrova, Liudmila A., et al.
Publicado: (2022)

An Efficient and Facile Methodology for Bromination of Pyrimidine and Purine Nucleosides with Sodium Monobromoisocyanurate (SMBI)
por: Maity, Jyotirmoy, et al.
Publicado: (2013)

In-Cell Trityl–Trityl Distance Measurements on Proteins
por: Yang, Yin, et al.
Publicado: (2020)

Solution-Phase Parallel Synthesis of Acyclic Nucleoside Libraries of Purine, Pyrimidine, and Triazole Acetamides
por: Pathak, Ashish K., et al.
Publicado: (2014)

Effect of Purine Nucleoside Analogue-Acyclovir on The Sperm Parameters and Testosterone Production in Rats
por: Movahed, Elham, et al.
Publicado: (2013)

Current Status of Older and New Purine Nucleoside Analogues in the Treatment of Lymphoproliferative Diseases
por: Robak, Tadeusz, et al.
Publicado: (2009)

Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations
por: Yehia, Heba, et al.
Publicado: (2020)

Synthesis and Characterization of NUC-7738, an Aryloxy Phosphoramidate of 3′-Deoxyadenosine, as a Potential Anticancer Agent
por: Serpi, Michaela, et al.
Publicado: (2022)

Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro
por: Thames, Joy E., et al.
Publicado: (2020)

Chapter 2: Ring-Expanded (‘Fat‘) Purines and their Nucleoside/Nucleotide Analogues as Broad-Spectrum Therapeutics
por: Hosmane, Ramachandra S.
Publicado: (2009)

Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water
por: Roberts, Samuel J., et al.
Publicado: (2018)

Nucleoside Transport and Nucleobase Uptake Null Mutants in Leishmania mexicana for the Routine Expression and Characterization of Purine and Pyrimidine Transporters
por: Aldfer, Mustafa M., et al.
Publicado: (2022)

Novel Nucleoside Analogues as Effective Antiviral Agents for Zika Virus Infections
por: Bassetto, Marcella, et al.
Publicado: (2020)

Purine nucleosides: endogenous neuroprotectants in hypoxic brain
por: Thauerer, Bettina, et al.
Publicado: (2012)

Efficient Synthesis of Purine Nucleoside Analogs by a New Trimeric Purine Nucleoside Phosphorylase from Aneurinibacillus migulanus AM007
por: Liu, Gaofei, et al.
Publicado: (2019)

Validation of Plasmodium falciparum dUTPase as the target of 5′-tritylated deoxyuridine analogues with anti-malarial activity
por: Pérez-Moreno, Guiomar, et al.
Publicado: (2019)

Synthesis, cytostatic and anti-HIV evaluations of the new unsaturated acyclic C-5 pyrimidine nucleoside analogues
por: Gazivoda, Tatjana, et al.
Publicado: (2008)

Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues
por: Andreeva, Olga V., et al.
Publicado: (2021)

A promising strategy against SARS-CoV-2: pyrimidine inhibitors synergize with nucleoside analogues
por: Min, Long, et al.
Publicado: (2022)

Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model
por: Cassera, María B., et al.
Publicado: (2011)

Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents
por: Bassetto, Marcella, et al.
Publicado: (2017)

Stretches of alternating pyrimidine/purines and purines are respectively linked with pathogenicity and growth temperature in prokaryotes
por: Bohlin, Jon, et al.
Publicado: (2009)

Purine nucleoside phosphorylase is associated with centrioles and basal bodies
Publicado: (1981)

Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases
por: Chaikuad, Apirat, et al.
Publicado: (2009)

Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
por: Almendros, Marcos, et al.
Publicado: (2009)

The Effects of Injection of Purine and Pyrimidine Compounds on Grafted Mice
por: Barker, G. R., et al.
Publicado: (1949)

PURINE AND PYRIMIDINE CONTENTS OF SOME DESOXYPENTOSE NUCLEIC ACIDS
por: Daly, M. M., et al.
Publicado: (1950)

Abiotic synthesis of purine and pyrimidine ribonucleosides in aqueous microdroplets
por: Nam, Inho, et al.
Publicado: (2018)

A Prebiotic Synthesis of Canonical Pyrimidine and Purine Ribonucleotides
por: Kim, Hyo-Joong, et al.
Publicado: (2019)

Investigation of pyrimidine nucleoside analogues as chemical probes to assess compound effects on the proliferation of Trypanosoma cruzi intracellular parasites
por: Sykes, Melissa Louise, et al.
Publicado: (2020)

N-Trityl-2-(tritylsulfanyl)aniline
por: Neuba, Adam, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_bfcdeuh2840et1e70p7r4to7eo