Cargando…

Enzymatic Strategy for the Resolution of New 1‐Hydroxymethyl Tetrahydro‐β‐carboline Derivatives in Batch and Continuous‐Flow Systems

Many alkaloids containing a tetrahydro‐β‐carboline skeleton have well‐known therapeutic effects, leading to increased interest in the synthesis of these natural products. Enantiomers of N‐Boc‐protected 1‐hydroxymethyl‐1,2,3,4‐tetrahydro‐β‐carboline [(±)‐7], 1‐hydroxymethyl‐6‐methoxy‐1,2,3,4‐tetrahyd...

Descripción completa

Detalles Bibliográficos
Autores principales:	Megyesi, Rita, Forró, Enikő, Fülöp, Ferenc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984410/ https://www.ncbi.nlm.nih.gov/pubmed/27551661 http://dx.doi.org/10.1002/open.201500203

Ejemplares similares

Efficient Enzymatic Routes for the Synthesis of New Eight-Membered Cyclic β-Amino Acid and β-Lactam Enantiomers
por: Forró, Enikő, et al.
Publicado: (2017)

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors
por: Abadi, Ashraf H., et al.
Publicado: (2011)

Electrochemical oxidative rearrangement of tetrahydro-β-carbolines in a zero-gap flow cell
por: Zheng, Yiting, et al.
Publicado: (2022)

Novel stereocontrolled syntheses of tashiromine and epitashiromine
por: Kiss, Loránd, et al.
Publicado: (2015)

The diketopiperazine-fused tetrahydro-β-carboline scaffold as a model peptidomimetic with an unusual α-turn secondary structure
por: Airaghi, Francesco, et al.
Publicado: (2013)

Synthesis and biological activity of N-substituted-tetrahydro-γ-carbolines containing peptide residues
por: Sokolova, Nadezhda V, et al.
Publicado: (2014)

Direct Enzymatic Route for the Preparation of Novel Enantiomerically Enriched Hydroxylated β-Amino Ester Stereoisomers
por: Forró, Enikő, et al.
Publicado: (2010)

Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines
por: Jaromin, Anna, et al.
Publicado: (2021)

Synthesis of tetrahydro-β-carbolines from 2-indolylmethyl azides and propargylic alcohols
por: Yin, Haiting, et al.
Publicado: (2021)

Synthesis and Investigation of Tetrahydro-β-carboline Derivatives as Inhibitors of Plant Pathogenic Fungi
por: Buaban, Koonchira, et al.
Publicado: (2021)

Efficient Synthesis of New Fluorinated β-Amino Acid Enantiomers through Lipase-Catalyzed Hydrolysis
por: Shahmohammadi, Sayeh, et al.
Publicado: (2020)

Discovery of Novel Tetrahydro-β-carboline Containing Aminopeptidase N Inhibitors as Cancer Chemosensitizers
por: Xing, Xiaoyan, et al.
Publicado: (2022)

Synthesis and Antibacterial Study of Novel Harmine Derivatives and Tetrahydro-β-Carboline Derivatives In Vitro
por: Liang, Yan, et al.
Publicado: (2022)

Bismuth Subnitrate-Catalyzed Markovnikov-Type Alkyne Hydrations under Batch and Continuous Flow Conditions
por: Szécsényi, Zsanett, et al.
Publicado: (2021)

Stereo- and Regiocontrolled Syntheses of Exomethylenic Cyclohexane β-Amino Acid Derivatives
por: Kiss, Loránd, et al.
Publicado: (2015)

Pharmacological Importance of Optically Active Tetrahydro-β-carbolines and Synthetic Approaches to Create the C1 Stereocenter
por: Laine, Aino E., et al.
Publicado: (2014)

A facile and efficient method for the synthesis of crystalline tetrahydro-β-carbolines via the Pictet-Spengler reaction in water
por: Byeon, Hong-Ju, et al.
Publicado: (2020)

Diastereoselective approach to rationally design tetrahydro-β-carboline–isatin conjugates as potential SERMs against breast cancer
por: Sharma, Bharvi, et al.
Publicado: (2019)

TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline
por: Sathish, Manda, et al.
Publicado: (2021)

Design, Synthesis, Antiproliferative Evaluation, and Molecular Docking Studies of N-(3-Hydroxyindole)-Appended β-Carbolines/Tetrahydro-β-Carbolines Targeting Triple-Negative and Non-Triple-Negative Breast Cancer
por: Sharma, Bharvi, et al.
Publicado: (2020)

Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction
por: Xu, Shi-Ming, et al.
Publicado: (2019)

Enzymatic separation of epimeric 4-C-hydroxymethylated furanosugars: Synthesis of bicyclic nucleosides
por: Rana, Neha, et al.
Publicado: (2017)

Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production
por: Ötvös, Sándor B, et al.
Publicado: (2013)

Oxidative Asymmetric Formal Aza-Diels–Alder Reactions of Tetrahydro-β-carboline with Enones in the Synthesis of Indoloquinolizidine-2-ones
por: Wu, Xiang, et al.
Publicado: (2018)

Comparison of the Inhibitory Binding Modes Between the Planar Fascaplysin and Its Nonplanar Tetrahydro-β-carboline Analogs in CDK4
por: Liang, Yan, et al.
Publicado: (2021)

Continuous-flow retro-Diels–Alder reaction: an efficient method for the preparation of pyrimidinone derivatives
por: Nekkaa, Imane, et al.
Publicado: (2018)

Synthesis and in silico screening of a library of β-carboline-containing compounds
por: Brummond, Kay M, et al.
Publicado: (2012)

An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y
por: Meruva, Suresh Babu, et al.
Publicado: (2014)

Asymmetric Synthesis of (R)‐1‐Alkyl‐Substituted Tetrahydro‐ß‐carbolines Catalyzed by Strictosidine Synthases
por: Pressnitz, Desiree, et al.
Publicado: (2018)

Simultaneous Production of Psilocybin and a Cocktail of β‐Carboline Monoamine Oxidase Inhibitors in “Magic” Mushrooms
por: Blei, Felix, et al.
Publicado: (2019)

Immobilization of Phenylalanine Ammonia‐Lyase on Single‐Walled Carbon Nanotubes for Stereoselective Biotransformations in Batch and Continuous‐Flow Modes
por: Bartha‐Vári, Judith H., et al.
Publicado: (2015)

Carbazole and tetrahydro-carboline derivatives as dopamine D(3) receptor antagonists with the multiple antipsychotic-like properties
por: Li, Zhongtang, et al.
Publicado: (2023)

cis-(9S,10S)-Methyl 1-propyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylate
por: Alam, Samina, et al.
Publicado: (2008)

A Sustainable Green Enzymatic Method for Amide Bond Formation
por: Orsy, György, et al.
Publicado: (2023)

Synthesis of Biorenewable Terpene Monomers Using Enzymatic Epoxidation under Heterogeneous Batch and Continuous Flow Conditions
por: Brandolese, Arianna, et al.
Publicado: (2023)

Ingenine F: A New Cytotoxic Tetrahydro Carboline Alkaloid from the Indonesian Marine Sponge Acanthostrongylophora ingens
por: Ibrahim, Sabrin, et al.
Publicado: (2018)

Alterations of nocturnal activity in rats following subchronic oral administration of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline
por: Sontag, Thomas A., et al.
Publicado: (2009)

Determination of Structural Requirements of N-Substituted Tetrahydro-β-Carboline Imidazolium Salt Derivatives Using in Silico Approaches for Designing MEK-1 Inhibitors
por: Liang, Jingwei, et al.
Publicado: (2017)

Aza-Annulation of 1,2,3,4-Tetrahydro-β-carboline Derived Enaminones and Nitroenamines: Synthesis of Functionalized Indolizino[8,7-b]indoles, Pyrido[1,2-a:3,4-b′]diindoles, Indolo[2,3-a]quinolizidine-4-ones and Other Tetrahydro-β-carboline Fused Heterocycles
por: Avadhani, Anusha, et al.
Publicado: (2019)

Mechanochemical enzymatic resolution of N-benzylated-β(3)-amino esters
por: Pérez-Venegas, Mario, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vj2va192i08s4kd26ue0nj2p98