Cargando…

Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids

We previously reported that an amino acid substitution, Y704A, near the 2-fold interface of adeno-associated virus (AAV) was defective for transcription of the packaged genome (M. Salganik, F. Aydemir, H. J. Nam, R. McKenna, M. Agbandje-McKenna, and N. Muzyczka, J Virol 88:1071–1079, 2013, doi: http...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aydemir, Fikret, Salganik, Maxim, Resztak, Justyna, Singh, Jasbir, Bennett, Antonette, Agbandje-McKenna, Mavis, Muzyczka, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984656/ https://www.ncbi.nlm.nih.gov/pubmed/27252527 http://dx.doi.org/10.1128/JVI.00493-16

Ejemplares similares

Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor
por: Pillay, Sirika, et al.
Publicado: (2017)

Adeno-associated Virus (AAV) Capsid Chimeras with Enhanced Infectivity Reveal a Core Element in the AAV Genome Critical for both Cell Transduction and Capsid Assembly
por: Viney, Lydia, et al.
Publicado: (2021)

Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?
por: Aslanidi, George V., et al.
Publicado: (2013)

Receptor Switching in Newly Evolved Adeno-associated Viruses
por: Havlik, L. Patrick, et al.
Publicado: (2021)

Creating an arsenal of Adeno-associated virus (AAV) gene delivery stealth vehicles
por: Smith, J. Kennon, et al.
Publicado: (2018)

Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking
por: Lins-Austin, Bridget, et al.
Publicado: (2020)

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant
por: Tan, Yong Zi, et al.
Publicado: (2018)

Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors
por: Tseng, Yu-Shan, et al.
Publicado: (2014)

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS
por: Kanaan, Nicholas M., et al.
Publicado: (2017)

Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features
por: Mietzsch, Mario, et al.
Publicado: (2021)

Adeno-associated virus capsid assembly is divergent and stochastic
por: Wörner, Tobias P., et al.
Publicado: (2021)

Thermal Stability as a Determinant of AAV Serotype Identity
por: Bennett, Antonette, et al.
Publicado: (2017)

Differential effects of two MRI contrast agents on the integrity and distribution of rAAV2 and rAAV5 in the rat striatum
por: Osting, Sue, et al.
Publicado: (2014)

The Role of the Adeno-Associated Virus Capsid in Gene Transfer
por: Van Vliet, Kim M., et al.
Publicado: (2008)

Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints
por: Vandenberghe, Luk H., et al.
Publicado: (2009)

Site-Directed Mutagenesis Improves the Transduction Efficiency of Capsid Library-Derived Recombinant AAV Vectors
por: Ran, Gai, et al.
Publicado: (2020)

Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors
por: Kay, Christine N., et al.
Publicado: (2013)

Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard
por: Mietzsch, Mario, et al.
Publicado: (2023)

Correction: Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors
por: Kay, Christine N., et al.
Publicado: (2013)

Characterization of AAV-Specific Affinity Ligands: Consequences for Vector Purification and Development Strategies
por: Mietzsch, Mario, et al.
Publicado: (2020)

Adeno-Associated Virus VP1u Exhibits Protease Activity
por: Kurian, Justin J., et al.
Publicado: (2019)

Characterization of Naturally-Occurring Humoral Immunity to AAV in Sheep
por: Tellez, Joseph, et al.
Publicado: (2013)

Complex Interplay between HIV-1 Capsid and MX2-Independent Alpha Interferon-Induced Antiviral Factors
por: Bulli, Lorenzo, et al.
Publicado: (2016)

A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates
por: Wang, Dan, et al.
Publicado: (2018)

Tailoring the AAV2 capsid vector for bone-targeting
por: Alméciga-Díaz, Carlos J., et al.
Publicado: (2018)

Methylation Status of the Adeno-Associated Virus Type 2 (AAV2)
por: Tóth, Renáta, et al.
Publicado: (2019)

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2
por: Cabanes-Creus, Marti, et al.
Publicado: (2020)

Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity
por: Judd, Justin, et al.
Publicado: (2012)

Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry
por: Smith, Timothy J., et al.
Publicado: (2023)

Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex
por: Das, Anshuman, et al.
Publicado: (2022)

Gene Transfer in Rodent Nervous Tissue Following Hindlimb Intramuscular Delivery of Recombinant Adeno-Associated Virus Serotypes AAV2/6, AAV2/8, and AAV2/9
por: Jan, Asad, et al.
Publicado: (2019)

The Golgi Calcium ATPase Pump Plays an Essential Role in Adeno-associated Virus Trafficking and Transduction
por: Madigan, Victoria J., et al.
Publicado: (2020)

Evolution of dependoparvoviruses across geological timescales—implications for design of AAV-based gene therapy vectors
por: Hildebrandt, Evin, et al.
Publicado: (2020)

Adeno-Associated Virus Receptor-Binding: Flexible Domains and Alternative Conformations through Cryo-Electron Tomography of Adeno-Associated Virus 2 (AAV2) and AAV5 Complexes
por: Hu, Guiqing, et al.
Publicado: (2022)

Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid
por: Sultana, Tahmina, et al.
Publicado: (2019)

HIV-1 CA Inhibitors Are Antagonized by Inositol Phosphate Stabilization of the Viral Capsid in Cells
por: Sowd, Gregory A., et al.
Publicado: (2021)

Tracking the Replication-Competent Zika Virus with Tetracysteine-Tagged Capsid Protein in Living Cells
por: Li, Shimin, et al.
Publicado: (2022)

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes
por: Hui, Daniel J, et al.
Publicado: (2015)

Post‐translational modifications in capsid proteins of recombinant adeno‐associated virus (AAV) 1‐rh10 serotypes
por: Mary, Bertin, et al.
Publicado: (2019)

Human astrovirus capsid protein releases a membrane lytic peptide upon trypsin maturation
por: Ykema, Matthew, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lc4cshikcv1udbutesj1e1cbhj