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A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection

Rift Valley fever virus (RVFV) is an arbovirus within the Bunyaviridae family capable of causing serious morbidity and mortality in humans and livestock. To identify host factors involved in bunyavirus replication, we employed genome-wide RNA interference (RNAi) screening and identified 381 genes wh...

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Detalles Bibliográficos
Autores principales: Harmon, Brooke, Bird, Sara W., Schudel, Benjamin R., Hatch, Anson V., Rasley, Amy, Negrete, Oscar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984662/
https://www.ncbi.nlm.nih.gov/pubmed/27226375
http://dx.doi.org/10.1128/JVI.00543-16

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