Falling for the dark side of transcription: Nab2 fosters RNA polymerase III transcription

RNA polymerase III (RNAPIII) synthesizes diverse, small, non-coding RNAs with many important roles in the cellular metabolism. One of the open questions of RNAPIII transcription is whether and how additional factors are involved. Recently, Nab2 was identified as the first messenger ribonucleoprotein...

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Detalles Bibliográficos
Autores principales: Reuter, L. Maximilian, Sträßer, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984684/
https://www.ncbi.nlm.nih.gov/pubmed/27049816
http://dx.doi.org/10.1080/21541264.2016.1170252
Descripción
Sumario:RNA polymerase III (RNAPIII) synthesizes diverse, small, non-coding RNAs with many important roles in the cellular metabolism. One of the open questions of RNAPIII transcription is whether and how additional factors are involved. Recently, Nab2 was identified as the first messenger ribonucleoprotein particle (mRNP) biogenesis factor with a function in RNAPIII transcription.

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