BRAF-V600E expression in primary nodular melanoma is associated with aggressive tumour features and reduced survival

BACKGROUND: Around 50% of primary melanomas harbour BRAF mutations, but their prognostic impact has not been clear. Recently, a BRAF-V600E mutation-specific antibody has become available for immunohistochemistry. Here, we investigated for the first time the prognostic impact of BRAF-V600E protein ex...

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Detalles Bibliográficos
Autores principales: Hugdahl, Emilia, Kalvenes, May Britt, Puntervoll, Hanne E, Ladstein, Rita G, Akslen, Lars A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984864/
https://www.ncbi.nlm.nih.gov/pubmed/26924424
http://dx.doi.org/10.1038/bjc.2016.44

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