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Uncovering the Thermodynamics of Monomer Binding for RNA Replication

[Image: see text] The nonenzymatic replication of primordial RNA is thought to have been a critical step in the origin of life. However, despite decades of effort, the poor rate and fidelity of model template copying reactions have thus far prevented an experimental demonstration of nonenzymatic RNA...

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Detalles Bibliográficos
Autores principales: Izgu, Enver Cagri, Fahrenbach, Albert C., Zhang, Na, Li, Li, Zhang, Wen, Larsen, Aaron T., Blain, J. Craig, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984997/
https://www.ncbi.nlm.nih.gov/pubmed/25901790
http://dx.doi.org/10.1021/jacs.5b02707