Cargando…

Uncovering the Thermodynamics of Monomer Binding for RNA Replication

[Image: see text] The nonenzymatic replication of primordial RNA is thought to have been a critical step in the origin of life. However, despite decades of effort, the poor rate and fidelity of model template copying reactions have thus far prevented an experimental demonstration of nonenzymatic RNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Izgu, Enver Cagri, Fahrenbach, Albert C., Zhang, Na, Li, Li, Zhang, Wen, Larsen, Aaron T., Blain, J. Craig, Szostak, Jack W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984997/ https://www.ncbi.nlm.nih.gov/pubmed/25901790 http://dx.doi.org/10.1021/jacs.5b02707

Ejemplares similares

Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer–Template Complexes
por: Tam, Chun Pong, et al.
Publicado: (2017)

Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization
por: Larsen, Aaron T., et al.
Publicado: (2015)

DNA polymerase activity on synthetic N3′→P5′ phosphoramidate DNA templates
por: Lelyveld, Victor S, et al.
Publicado: (2019)

N-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes
por: Izgu, Enver Cagri, et al.
Publicado: (2016)

Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides
por: Li, Li, et al.
Publicado: (2017)

Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers
por: Schrum, Jason P., et al.
Publicado: (2009)

Oligoarginine Peptides Slow Strand Annealing and Assist Nonenzymatic RNA Replication
por: Jia, Tony Z., et al.
Publicado: (2016)

Unusual Base-Pairing Interactions in Monomer–Template Complexes
por: Zhang, Wen, et al.
Publicado: (2016)

Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs
por: Sheng, Jia, et al.
Publicado: (2014)

Synthesis of N3′-P5′-linked Phosphoramidate DNA by Nonenzymatic Template-Directed Primer Extension
por: Zhang, Shenglong, et al.
Publicado: (2012)

Synthesis of a Nonhydrolyzable Nucleotide Phosphoroimidazolide Analogue That Catalyzes Nonenzymatic RNA Primer Extension
por: Tam, Chun Pong, et al.
Publicado: (2017)

Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis
por: Kwiatek, Joanna M., et al.
Publicado: (2022)

Interactions between Fkh1 monomers stabilize its binding to DNA replication origins
por: Reinapae, Allan, et al.
Publicado: (2023)

Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation
por: Fahrenbach, Albert C., et al.
Publicado: (2017)

Synthesis and Nonenzymatic Template-Directed Polymerization of 2′-Amino-2′-deoxythreose Nucleotides
por: Blain, J. Craig, et al.
Publicado: (2014)

Handcuffing reversal is facilitated by proteases and replication initiator monomers
por: Bury, Katarzyna, et al.
Publicado: (2017)

Replication regulation of Vibrio cholerae chromosome II involves initiator binding to the origin both as monomer and as dimer
por: Jha, Jyoti K., et al.
Publicado: (2012)

Ultraviolet-Driven Deamination of Cytidine Ribonucleotides Under Planetary Conditions
por: Todd, Zoe R., et al.
Publicado: (2020)

Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides
por: Prywes, Noam, et al.
Publicado: (2016)

Activated Ribonucleotides Undergo a Sugar Pucker Switch upon Binding to a Single-Stranded RNA Template
por: Zhang, Na, et al.
Publicado: (2012)

Solvated-electron production using cyanocuprates is compatible with the UV-environment on a Hadean–Archaean Earth
por: Todd, Zoe R., et al.
Publicado: (2018)

High-avidity binding drives nucleation of amyloidogenic transthyretin monomer
por: Gao, Li, et al.
Publicado: (2022)

Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics
por: Wang, Yong, et al.
Publicado: (2017)

Bidirectional Direct Sequencing of Noncanonical RNA by Two-Dimensional Analysis of Mass Chromatograms
por: Björkbom, Anders, et al.
Publicado: (2015)

Thermodynamically stable amyloid-β monomers have much lower membrane affinity than the small oligomers
por: Sarkar, Bidyut, et al.
Publicado: (2013)

The virtual circular genome model for primordial RNA replication
por: Zhou, Lijun, et al.
Publicado: (2021)

Transfer of Sequence Information and Replication of Diimine Duplexes
por: Strom, Kyle R., et al.
Publicado: (2019)

Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding
por: Martinez Fiesco, Juliana A., et al.
Publicado: (2022)

Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers
por: Bing, Tao, et al.
Publicado: (2019)

Binding Thermodynamics and Dissociation Kinetics Analysis Uncover the Key Structural Motifs of Phenoxyphenol Derivatives as the Direct InhA Inhibitors and the Hotspot Residues of InhA
por: Zhang, Qianqian, et al.
Publicado: (2022)

Interdomain dynamics in human Replication Protein A regulates kinetics and thermodynamics of its binding to ssDNA
por: Sangeeta,, et al.
Publicado: (2023)

Entropy in specificity and thermodynamics of binding
por: Liedl, Klaus R
Publicado: (2014)

Structural Ensemble of the Insulin Monomer
por: Busto-Moner, Luis, et al.
Publicado: (2021)

Stratum corneum lipid liposome-encapsulated panomycocin: preparation, characterization, and the determination of antimycotic efficacy against Candida spp. isolated from patients with vulvovaginitis in an in vitro human vaginal epithelium tissue model
por: İzgü, Fatih, et al.
Publicado: (2017)

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils
por: Agerschou, Emil Dandanell, et al.
Publicado: (2019)

Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication
por: Ding, Dian, et al.
Publicado: (2023)

Thermodynamics
por: Holman, J. P. (Jack Philip)
Publicado: (1980)

Thermodynamics
por: Holman, J. P. (Jack Philip)
Publicado: (1974)

Perturbation of the Monomer–Monomer Interfaces of the Benzoylformate Decarboxylase Tetramer
por: Andrews, Forest H., et al.
Publicado: (2014)

Redesign of the monomer–monomer interface of Cre recombinase yields an obligate heterotetrameric complex
por: Zhang, Chi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_i5lf95d12r5d2i4f36jm4rv2i9