Cargando…
Genetic Panel Screening of Nearly 100 Mutations Reveals New Insights into the Breed Distribution of Risk Variants for Canine Hereditary Disorders
BACKGROUND: The growing number of identified genetic disease risk variants across dog breeds challenges the current state-of-the-art of population screening, veterinary molecular diagnostics, and genetic counseling. Multiplex screening of such variants is now technologically feasible, but its practi...
Autores principales: | Donner, Jonas, Kaukonen, Maria, Anderson, Heidi, Möller, Fredrik, Kyöstilä, Kaisa, Sankari, Satu, Hytönen, Marjo, Giger, Urs, Lohi, Hannes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985128/ https://www.ncbi.nlm.nih.gov/pubmed/27525650 http://dx.doi.org/10.1371/journal.pone.0161005 |
Ejemplares similares
-
An across-breed validation study of 46 genetic markers in canine hip dysplasia
por: Mikkola, Lea, et al.
Publicado: (2021) -
Intronic variant in POU1F1 associated with canine pituitary dwarfism
por: Kyöstilä, Kaisa, et al.
Publicado: (2021) -
A putative silencer variant in a spontaneous canine model of retinitis pigmentosa
por: Kaukonen, Maria, et al.
Publicado: (2020) -
A homozygous missense variant in the alkaline phosphatase gene ALPL is associated with a severe form of canine hypophosphatasia
por: Kyöstilä, Kaisa, et al.
Publicado: (2019) -
Canine Chondrodysplasia Caused by a Truncating Mutation in Collagen-Binding Integrin Alpha Subunit 10
por: Kyöstilä, Kaisa, et al.
Publicado: (2013)