Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Atherosclerosis results from maladaptive inflammation driven primarily by macrophages, whose recruitment and proliferation drive plaque progression. In advanced plaques, macrophage death contributes centrally to the formation of plaque necrosis, which underlies the instability that promotes plaque r...

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Detalles Bibliográficos
Autores principales: Karunakaran, Denuja, Geoffrion, Michele, Wei, Lihui, Gan, Wei, Richards, Laura, Shangari, Prakriti, DeKemp, Ella M., Beanlands, Rachelle A., Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Sad, Subash, Guo, Liang, Kolodgie, Frank D., Virmani, Renu, Ruddy, Terrence, Rayner, Katey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985228/
https://www.ncbi.nlm.nih.gov/pubmed/27532042
http://dx.doi.org/10.1126/sciadv.1600224

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