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Prospective changes in global DNA methylation and cancer incidence and mortality

BACKGROUND: Methylation of repetitive elements Alu and LINE-1 in humans is considered a surrogate for global DNA methylation. Previous studies of blood-measured Alu/LINE-1 and cancer risk are inconsistent. METHODS: We studied 1259 prospective methylation measurements from blood drawn 1–4 times from...

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Detalles Bibliográficos
Autores principales:	Joyce, Brian T, Gao, Tao, Zheng, Yinan, Liu, Lei, Zhang, Wei, Dai, Qi, Shrubsole, Martha J, Hibler, Elizabeth A, Cristofanilli, Massimo, Zhang, Hu, Yang, Hushan, Vokonas, Pantel, Cantone, Laura, Schwartz, Joel, Baccarelli, Andrea, Hou, Lifang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985350/ https://www.ncbi.nlm.nih.gov/pubmed/27351216 http://dx.doi.org/10.1038/bjc.2016.205

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