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Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo
The blockade of phagolysosomal fusion is considered a critical mycobacterial strategy to survive in macrophages. However, viable mycobacteria have been observed in phagolysosomes during infection of cultured macrophages, and mycobacteria have the virulence determinant MarP, which confers acid resist...
Autores principales: | Levitte, Steven, Adams, Kristin N., Berg, Russell D., Cosma, Christine L., Urdahl, Kevin B., Ramakrishnan, Lalita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985559/ https://www.ncbi.nlm.nih.gov/pubmed/27512905 http://dx.doi.org/10.1016/j.chom.2016.07.007 |
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