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HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway

HIV-1 transactivator protein (Tat) has been shown to play an important role in HIV-associated neurocognitive disorders. The aim of the present study was to evaluate the relationship between occludin and amyloid-beta (Aβ) transfer receptors in human cerebral microvascular endothelial cells (hCMEC/D3)...

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Detalles Bibliográficos
Autores principales: Chen, Yanlan, Huang, Wen, Jiang, Wenlin, Wu, Xianghong, Ye, Biao, Zhou, Xiaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985576/
https://www.ncbi.nlm.nih.gov/pubmed/27563375
http://dx.doi.org/10.1155/2016/4196572

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