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Ligustrazine Inhibits Cartilage Endplate Hypertrophy via Suppression of TGF-β1

CEP hypertrophy is one of the characteristics of intervertebral disc degeneration (IDD). LIG exerts a protective effect on IDD in animal model. The effect of LIG on CEP hypertrophy is further investigated in the present study. Cells were isolated from hypertrophic samples obtained from patients duri...

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Detalles Bibliográficos
Autores principales: Liu, Shufen, Zhao, Bizeng, Shi, Huipeng, Liang, Qianqian, Fu, Yishan, Yang, Zhu, Xu, Leqin, Wang, Yongjun, Bian, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985580/
https://www.ncbi.nlm.nih.gov/pubmed/27563332
http://dx.doi.org/10.1155/2016/1042489