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Refactoring the λ phage lytic/lysogenic decision with a synthetic regulator
In this work, we explore the refactoring of the circuitry of λ phage by engineering a new‐to‐nature regulator that responds to an ad hoc input signal that behaves orthogonal with respect to the host cell. We tailored a chimeric regulator, termed Qλ, between the CI protein of the λ phage and the BzdR...
Autores principales: | Durante‐Rodríguez, Gonzalo, Mancheño, José Miguel, Díaz, Eduardo, Carmona, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985591/ https://www.ncbi.nlm.nih.gov/pubmed/26987659 http://dx.doi.org/10.1002/mbo3.352 |
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