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Ribonuclease 5 facilitates corneal endothelial wound healing via activation of PI3-kinase/Akt pathway

To maintain corneal transparency, corneal endothelial cells (CECs) exert a pump function against aqueous inflow. However, human CECs are arrested in the G(1)-phase and non-proliferative in vivo. Thus, treatment of corneal endothelial decompensation is limited to corneal transplantation, and grafts a...

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Detalles Bibliográficos
Autores principales: Kim, Kyoung Woo, Park, Soo Hyun, Lee, Soo Jin, Kim, Jae Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985649/
https://www.ncbi.nlm.nih.gov/pubmed/27526633
http://dx.doi.org/10.1038/srep31162