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Proteomic differences in recombinant CHO cells producing two similar antibody fragments
Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the production of biopharmaceuticals. To overcome unfavorable features of CHO cells, a lot of effort is put into cell engineering to improve phenotype. “Omics” studies investigating elevated growth rate and specific pro...
Autores principales: | Sommeregger, Wolfgang, Mayrhofer, Patrick, Steinfellner, Willibald, Reinhart, David, Henry, Michael, Clynes, Martin, Meleady, Paula, Kunert, Renate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985663/ https://www.ncbi.nlm.nih.gov/pubmed/26913574 http://dx.doi.org/10.1002/bit.25957 |
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