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Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex

Small changes in DNA sequence can often have major biological effects. Here the rates and yields of guanine photo‐oxidation by Λ‐[Ru(TAP)(2)(dppz)](2+) have been compared in 5′‐{CCGGATCCGG}(2) and 5′‐{CCGGTACCGG}(2) using pico/nanosecond transient visible and time‐resolved IR (TRIR) spectroscopy. Th...

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Detalles Bibliográficos
Autores principales:	Keane, Páraic M., Poynton, Fergus E., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY‐VCH Verlag 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985698/ https://www.ncbi.nlm.nih.gov/pubmed/26096623 http://dx.doi.org/10.1002/anie.201502608

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