Negative Feedback Regulation of HIV-1 by Gene Editing Strategy

The CRISPR/Cas9 gene editing method is comprised of the guide RNA (gRNA) to target a specific DNA sequence for cleavage and the Cas9 endonuclease for introducing breaks in the double-stranded DNA identified by the gRNA. Co-expression of both a multiplex of HIV-1-specific gRNAs and Cas9 in cells resu...

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Detalles Bibliográficos
Autores principales: Kaminski, Rafal, Chen, Yilan, Salkind, Julian, Bella, Ramona, Young, Won-bin, Ferrante, Pasquale, Karn, Jonathan, Malcolm, Thomas, Hu, Wenhui, Khalili, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985742/
https://www.ncbi.nlm.nih.gov/pubmed/27528385
http://dx.doi.org/10.1038/srep31527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985742/
https://www.ncbi.nlm.nih.gov/pubmed/27528385
http://dx.doi.org/10.1038/srep31527

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