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The deficiency of galectin-3 in stromal cells leads to enhanced tumor growth and bone marrow metastasis
BACKGROUND: Galectin-3 is a multifunctional β-galactoside-binding lectin that once synthesized, is expressed in the nucleus, cytoplasm, cell surface and in the extracellular environment. Because of its unique structure, galectin-3 can oligomerize forming lattice upon binding to multivalent oligossac...
Autores principales: | Pereira, Jonathas Xavier, Azeredo, Maria Carolina Braga, Martins, Felipe Sá, Chammas, Roger, Oliveira, Felipe Leite, Santos, Sofia Nascimento, Bernardes, Emerson Soares, El-Cheikh, Márcia Cury |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986277/ https://www.ncbi.nlm.nih.gov/pubmed/27526676 http://dx.doi.org/10.1186/s12885-016-2679-1 |
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