Highly activated p53 contributes to selectively increased apoptosis of latently HIV-1 infected cells upon treatment of anticancer drugs

BACKGROUND: Despite the successful inhibition of human immunodeficiency virus type 1 (HIV-1) replication by combination antiretroviral therapy, cells latently infected with HIV-1 remaining in patients are a major obstacle for eradication of HIV-1 infection. The tumor suppressor factor p53 is activat...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, YoungHyun, Lim, Hoyong, Choi, Byeong-Sun, Kim, Kyung-Chang, Kang, Chun, Bae, Yong-Soo, Yoon, Cheol-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986278/
https://www.ncbi.nlm.nih.gov/pubmed/27527606
http://dx.doi.org/10.1186/s12985-016-0595-2

Ejemplares similares

Ejemplares similares