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Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer
INTRODUCTION: One of the factors responsible for the risk of recurrence after complete transurethral resection of the bladder tumor (TURBT) in patients with non-muscle invasive bladder cancer (NMIBC) is the quality of surgery that may vary between individual surgeons. The aim of the study was to eva...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Polish Urological Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986305/ https://www.ncbi.nlm.nih.gov/pubmed/27551554 http://dx.doi.org/10.5173/ceju.2016.795 |
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author | Rolevich, Alexander Minich, Alexander Nabebina, Tatiana Polyakov, Sergey Krasny, Sergey Sukonko, Oleg |
author_facet | Rolevich, Alexander Minich, Alexander Nabebina, Tatiana Polyakov, Sergey Krasny, Sergey Sukonko, Oleg |
author_sort | Rolevich, Alexander |
collection | PubMed |
description | INTRODUCTION: One of the factors responsible for the risk of recurrence after complete transurethral resection of the bladder tumor (TURBT) in patients with non-muscle invasive bladder cancer (NMIBC) is the quality of surgery that may vary between individual surgeons. The aim of the study was to evaluate the impact of the surgeon on recurrence-free survival in patients with NMIBC. MATERIAL AND METHODS: The long-term results of a series of consecutive TURBTs performed by five staff urologists at a single institution were retrospectively analyzed. A total of 949 cases of organ-preserving treatment in 784 patients with NMIBC were included in the analysis. RESULTS: With the median follow-up of 64.3 months (3–124 months), the 5-year recurrence-free survival rates according to the surgeon were 62.9% (95% CI 56.2–69.7%), 53.6% (95% CI 47.4–59.9%), 51.0% (95% CI 39.6–62.4%), 46.2% (95% CI 36.4–56.0%), and 44.2% (95% CI 36.8–51.7%), respectively (p <0.0001). In the multivariate analysis including all potential risk factors, the individual surgeon was associated with a risk of recurrence with a high degree of statistical significance (p = 0.0013). The between-surgeon differences in the recurrence risk were not that pronounced in less extensive tumors. CONCLUSIONS: A surgeon has a significant impact on the risk of recurrence after curative treatment of patients with NMIBC. This effect was observed despite the relatively extensive experience in bladder endoscopic surgery of all of the surgeons and practicing in a setting of one specialized center. These findings should be taken into account while performing and evaluating the results of comparative studies. |
format | Online Article Text |
id | pubmed-4986305 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Polish Urological Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-49863052016-08-22 Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer Rolevich, Alexander Minich, Alexander Nabebina, Tatiana Polyakov, Sergey Krasny, Sergey Sukonko, Oleg Cent European J Urol Original Paper INTRODUCTION: One of the factors responsible for the risk of recurrence after complete transurethral resection of the bladder tumor (TURBT) in patients with non-muscle invasive bladder cancer (NMIBC) is the quality of surgery that may vary between individual surgeons. The aim of the study was to evaluate the impact of the surgeon on recurrence-free survival in patients with NMIBC. MATERIAL AND METHODS: The long-term results of a series of consecutive TURBTs performed by five staff urologists at a single institution were retrospectively analyzed. A total of 949 cases of organ-preserving treatment in 784 patients with NMIBC were included in the analysis. RESULTS: With the median follow-up of 64.3 months (3–124 months), the 5-year recurrence-free survival rates according to the surgeon were 62.9% (95% CI 56.2–69.7%), 53.6% (95% CI 47.4–59.9%), 51.0% (95% CI 39.6–62.4%), 46.2% (95% CI 36.4–56.0%), and 44.2% (95% CI 36.8–51.7%), respectively (p <0.0001). In the multivariate analysis including all potential risk factors, the individual surgeon was associated with a risk of recurrence with a high degree of statistical significance (p = 0.0013). The between-surgeon differences in the recurrence risk were not that pronounced in less extensive tumors. CONCLUSIONS: A surgeon has a significant impact on the risk of recurrence after curative treatment of patients with NMIBC. This effect was observed despite the relatively extensive experience in bladder endoscopic surgery of all of the surgeons and practicing in a setting of one specialized center. These findings should be taken into account while performing and evaluating the results of comparative studies. Polish Urological Association 2016-04-19 2016 /pmc/articles/PMC4986305/ /pubmed/27551554 http://dx.doi.org/10.5173/ceju.2016.795 Text en Copyright by Polish Urological Association http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Original Paper Rolevich, Alexander Minich, Alexander Nabebina, Tatiana Polyakov, Sergey Krasny, Sergey Sukonko, Oleg Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
title | Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
title_full | Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
title_fullStr | Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
title_full_unstemmed | Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
title_short | Surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
title_sort | surgeon has a major impact on long-term recurrence risk in patients with non-muscle invasive bladder cancer |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986305/ https://www.ncbi.nlm.nih.gov/pubmed/27551554 http://dx.doi.org/10.5173/ceju.2016.795 |
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