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Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986358/ https://www.ncbi.nlm.nih.gov/pubmed/27526941 http://dx.doi.org/10.1186/s12879-016-1768-8 |
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author | Sama, Carlson–Babila Mbarga, Nicole Fouda Oben, Calvin Eta Mbarga, Jules A. Nfor, Elvis Kiloh Angwafo III, Fru F. |
author_facet | Sama, Carlson–Babila Mbarga, Nicole Fouda Oben, Calvin Eta Mbarga, Jules A. Nfor, Elvis Kiloh Angwafo III, Fru F. |
author_sort | Sama, Carlson–Babila |
collection | PubMed |
description | BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African female who presented with a chronic disfiguring cervical mass evolving over a 9 months period for which she had several unyielding consultations. Appropriate clinical and para-clinical evaluations were paramount to the diagnosis of an Actinomyces infection. We review the literature on its epidemiology, clinical presentation, diagnosis, treatment and prognosis. CONCLUSION: Actinomycosis still poses a diagnostic challenge. It is important for clinicians to consider the possibility of such rare infections in apparently malignant looking masses and also in lesions not responding to several antimicrobial treatments. The condition generally carries a good prognosis if recognised early and histopathological diagnosis is the gold standard. |
format | Online Article Text |
id | pubmed-4986358 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49863582016-08-22 Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy Sama, Carlson–Babila Mbarga, Nicole Fouda Oben, Calvin Eta Mbarga, Jules A. Nfor, Elvis Kiloh Angwafo III, Fru F. BMC Infect Dis Case Report BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African female who presented with a chronic disfiguring cervical mass evolving over a 9 months period for which she had several unyielding consultations. Appropriate clinical and para-clinical evaluations were paramount to the diagnosis of an Actinomyces infection. We review the literature on its epidemiology, clinical presentation, diagnosis, treatment and prognosis. CONCLUSION: Actinomycosis still poses a diagnostic challenge. It is important for clinicians to consider the possibility of such rare infections in apparently malignant looking masses and also in lesions not responding to several antimicrobial treatments. The condition generally carries a good prognosis if recognised early and histopathological diagnosis is the gold standard. BioMed Central 2016-08-15 /pmc/articles/PMC4986358/ /pubmed/27526941 http://dx.doi.org/10.1186/s12879-016-1768-8 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Sama, Carlson–Babila Mbarga, Nicole Fouda Oben, Calvin Eta Mbarga, Jules A. Nfor, Elvis Kiloh Angwafo III, Fru F. Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
title | Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
title_full | Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
title_fullStr | Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
title_full_unstemmed | Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
title_short | Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
title_sort | massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986358/ https://www.ncbi.nlm.nih.gov/pubmed/27526941 http://dx.doi.org/10.1186/s12879-016-1768-8 |
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