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Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy

BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African f...

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Autores principales: Sama, Carlson–Babila, Mbarga, Nicole Fouda, Oben, Calvin Eta, Mbarga, Jules A., Nfor, Elvis Kiloh, Angwafo III, Fru F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986358/
https://www.ncbi.nlm.nih.gov/pubmed/27526941
http://dx.doi.org/10.1186/s12879-016-1768-8
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author Sama, Carlson–Babila
Mbarga, Nicole Fouda
Oben, Calvin Eta
Mbarga, Jules A.
Nfor, Elvis Kiloh
Angwafo III, Fru F.
author_facet Sama, Carlson–Babila
Mbarga, Nicole Fouda
Oben, Calvin Eta
Mbarga, Jules A.
Nfor, Elvis Kiloh
Angwafo III, Fru F.
author_sort Sama, Carlson–Babila
collection PubMed
description BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African female who presented with a chronic disfiguring cervical mass evolving over a 9 months period for which she had several unyielding consultations. Appropriate clinical and para-clinical evaluations were paramount to the diagnosis of an Actinomyces infection. We review the literature on its epidemiology, clinical presentation, diagnosis, treatment and prognosis. CONCLUSION: Actinomycosis still poses a diagnostic challenge. It is important for clinicians to consider the possibility of such rare infections in apparently malignant looking masses and also in lesions not responding to several antimicrobial treatments. The condition generally carries a good prognosis if recognised early and histopathological diagnosis is the gold standard.
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spelling pubmed-49863582016-08-22 Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy Sama, Carlson–Babila Mbarga, Nicole Fouda Oben, Calvin Eta Mbarga, Jules A. Nfor, Elvis Kiloh Angwafo III, Fru F. BMC Infect Dis Case Report BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African female who presented with a chronic disfiguring cervical mass evolving over a 9 months period for which she had several unyielding consultations. Appropriate clinical and para-clinical evaluations were paramount to the diagnosis of an Actinomyces infection. We review the literature on its epidemiology, clinical presentation, diagnosis, treatment and prognosis. CONCLUSION: Actinomycosis still poses a diagnostic challenge. It is important for clinicians to consider the possibility of such rare infections in apparently malignant looking masses and also in lesions not responding to several antimicrobial treatments. The condition generally carries a good prognosis if recognised early and histopathological diagnosis is the gold standard. BioMed Central 2016-08-15 /pmc/articles/PMC4986358/ /pubmed/27526941 http://dx.doi.org/10.1186/s12879-016-1768-8 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sama, Carlson–Babila
Mbarga, Nicole Fouda
Oben, Calvin Eta
Mbarga, Jules A.
Nfor, Elvis Kiloh
Angwafo III, Fru F.
Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
title Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
title_full Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
title_fullStr Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
title_full_unstemmed Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
title_short Massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
title_sort massive paediatric cervicofacial actinomycoses masquerading as an ulcerative malignancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986358/
https://www.ncbi.nlm.nih.gov/pubmed/27526941
http://dx.doi.org/10.1186/s12879-016-1768-8
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