C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways

BACKGROUND: Proliferation of the vasa vasorum has been implicated in the pathogenesis of atherosclerosis, and the vasa vasorum is closely associated with resident stem cells within the vasculature. C-reactive protein (CRP) is positively correlated with cardiovascular disease risk, and our previous s...

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Detalles Bibliográficos
Autores principales: Chen, JiaYuan, Gu, ZhenJie, Wu, MaoXiong, Yang, Ying, Zhang, JianHua, Ou, JingSong, Zuo, ZhiYi, Wang, JingFeng, Chen, YangXin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986362/
https://www.ncbi.nlm.nih.gov/pubmed/27526687
http://dx.doi.org/10.1186/s13287-016-0377-1

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