A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

BACKGROUND: Preclinical studies have shown synergy between radiation therapy and immunotherapy. However, in almost all preclinical models, radiation is delivered in single doses or short courses of high doses (hypofractionated radiation). By contrast in most clinical settings, radiation is delivered...

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Detalles Bibliográficos
Autores principales: Crocenzi, Todd, Cottam, Benjamin, Newell, Pippa, Wolf, Ronald F., Hansen, Paul D., Hammill, Chet, Solhjem, Matthew C., To, Yue-Yun, Greathouse, Amy, Tormoen, Garth, Jutric, Zeljka, Young, Kristina, Bahjat, Keith S., Gough, Michael J., Crittenden, Marka R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986363/
https://www.ncbi.nlm.nih.gov/pubmed/27532020
http://dx.doi.org/10.1186/s40425-016-0149-6

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