Global Phylogenomic Analysis of Nonencapsulated Streptococcus pneumoniae Reveals a Deep-Branching Classic Lineage That Is Distinct from Multiple Sporadic Lineages

The surrounding capsule of Streptococcus pneumoniae has been identified as a major virulence factor and is targeted by pneumococcal conjugate vaccines (PCV). However, nonencapsulated S. pneumoniae (non-Ec-Sp) have also been isolated globally, mainly in carriage studies. It is unknown if non-Ec-Sp ev...

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Detalles Bibliográficos
Autores principales: Hilty, Markus, Wüthrich, Daniel, Salter, Susannah J., Engel, Hansjürg, Campbell, Samuel, Sá-Leão, Raquel, de Lencastre, Hermínia, Hermans, Peter, Sadowy, Ewa, Turner, Paul, Chewapreecha, Claire, Diggle, Mathew, Pluschke, Gerd, McGee, Lesley, Köseoğlu Eser, Özgen, Low, Donald E., Smith-Vaughan, Heidi, Endimiani, Andrea, Küffer, Marianne, Dupasquier, Mélanie, Beaudoing, Emmanuel, Weber, Johann, Bruggmann, Rémy, Hanage, William P., Parkhill, Julian, Hathaway, Lucy J., Mühlemann, Kathrin, Bentley, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986459/
https://www.ncbi.nlm.nih.gov/pubmed/25480686
http://dx.doi.org/10.1093/gbe/evu263

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