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Use of biosensors for the detection of marine toxins

Increasing occurrences of harmful algal blooms (HABs) in the ocean are a major concern for countries around the globe, and with strong links between HABs and climate change and eutrophication, the occurrences are only set to increase. Of particular concern with regard to HABs is the presence of toxi...

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Autores principales: McPartlin, Daniel A., Lochhead, Michael J., Connell, Laurie B., Doucette, Gregory J., O'Kennedy, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Limited 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986468/
https://www.ncbi.nlm.nih.gov/pubmed/27365035
http://dx.doi.org/10.1042/EBC20150006
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author McPartlin, Daniel A.
Lochhead, Michael J.
Connell, Laurie B.
Doucette, Gregory J.
O'Kennedy, Richard J.
author_facet McPartlin, Daniel A.
Lochhead, Michael J.
Connell, Laurie B.
Doucette, Gregory J.
O'Kennedy, Richard J.
author_sort McPartlin, Daniel A.
collection PubMed
description Increasing occurrences of harmful algal blooms (HABs) in the ocean are a major concern for countries around the globe, and with strong links between HABs and climate change and eutrophication, the occurrences are only set to increase. Of particular concern with regard to HABs is the presence of toxin-producing algae. Six major marine biotoxin groups are associated with HABs. Ingestion of such toxins via contaminated shellfish, fish, or other potential vectors, can lead to intoxication syndromes with moderate to severe symptoms, including death in extreme cases. There are also major economic implications associated with the diverse effects of marine biotoxins and HABs. Thus, effective monitoring programmes are required to manage and mitigate their detrimental global effect. However, currently legislated detection methods are labour-intensive, expensive and relatively slow. The growing field of biosensor diagnostic devices is an exciting area that has the potential to produce robust, easy-to-use, cost-effective, rapid and accurate detection methods for marine biotoxins and HABs. This review discusses recently developed biosensor assays that target marine biotoxins and their microbial producers, both in harvested fish/shellfish samples and in the open ocean. The effective deployment of such biosensor platforms could address the pressing need for improved monitoring of HABs and marine biotoxins, and could help to reduce their global economic impact.
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spelling pubmed-49864682016-08-29 Use of biosensors for the detection of marine toxins McPartlin, Daniel A. Lochhead, Michael J. Connell, Laurie B. Doucette, Gregory J. O'Kennedy, Richard J. Essays Biochem Article Increasing occurrences of harmful algal blooms (HABs) in the ocean are a major concern for countries around the globe, and with strong links between HABs and climate change and eutrophication, the occurrences are only set to increase. Of particular concern with regard to HABs is the presence of toxin-producing algae. Six major marine biotoxin groups are associated with HABs. Ingestion of such toxins via contaminated shellfish, fish, or other potential vectors, can lead to intoxication syndromes with moderate to severe symptoms, including death in extreme cases. There are also major economic implications associated with the diverse effects of marine biotoxins and HABs. Thus, effective monitoring programmes are required to manage and mitigate their detrimental global effect. However, currently legislated detection methods are labour-intensive, expensive and relatively slow. The growing field of biosensor diagnostic devices is an exciting area that has the potential to produce robust, easy-to-use, cost-effective, rapid and accurate detection methods for marine biotoxins and HABs. This review discusses recently developed biosensor assays that target marine biotoxins and their microbial producers, both in harvested fish/shellfish samples and in the open ocean. The effective deployment of such biosensor platforms could address the pressing need for improved monitoring of HABs and marine biotoxins, and could help to reduce their global economic impact. Portland Press Limited 2016-06-30 2016-06-30 /pmc/articles/PMC4986468/ /pubmed/27365035 http://dx.doi.org/10.1042/EBC20150006 Text en © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society
spellingShingle Article
McPartlin, Daniel A.
Lochhead, Michael J.
Connell, Laurie B.
Doucette, Gregory J.
O'Kennedy, Richard J.
Use of biosensors for the detection of marine toxins
title Use of biosensors for the detection of marine toxins
title_full Use of biosensors for the detection of marine toxins
title_fullStr Use of biosensors for the detection of marine toxins
title_full_unstemmed Use of biosensors for the detection of marine toxins
title_short Use of biosensors for the detection of marine toxins
title_sort use of biosensors for the detection of marine toxins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986468/
https://www.ncbi.nlm.nih.gov/pubmed/27365035
http://dx.doi.org/10.1042/EBC20150006
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