Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator

Medullary thymic epithelial cells (mTECs) expressing autoimmune regulator (Aire) are critical for preventing the onset of autoimmunity. However, the differentiation program of Aire-expressing mTECs (Aire(+) mTECs) is unclear. Here, we describe novel embryonic precursors of Aire(+) mTECs. We found th...

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Detalles Bibliográficos
Autores principales: Akiyama, Nobuko, Takizawa, Nobukazu, Miyauchi, Maki, Yanai, Hiromi, Tateishi, Ryosuke, Shinzawa, Miho, Yoshinaga, Riko, Kurihara, Masaaki, Demizu, Yosuke, Yasuda, Hisataka, Yagi, Shintaro, Wu, Guoying, Matsumoto, Mitsuru, Sakamoto, Reiko, Yoshida, Nobuaki, Penninger, Josef M., Kobayashi, Yasuhiro, Inoue, Jun-ichiro, Akiyama, Taishin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986530/
https://www.ncbi.nlm.nih.gov/pubmed/27401343
http://dx.doi.org/10.1084/jem.20151780

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