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Protection against malaria in mice is induced by blood stage–arresting histamine-releasing factor (HRF)–deficient parasites
Although most vaccines against blood stage malaria in development today use subunit preparations, live attenuated parasites confer significantly broader and more lasting protection. In recent years, Plasmodium genetically attenuated parasites (GAPs) have been generated in rodent models that cause se...
Autores principales: | Demarta-Gatsi, Claudia, Smith, Leanna, Thiberge, Sabine, Peronet, Roger, Commere, Pierre-Henri, Matondo, Mariette, Apetoh, Lionel, Bruhns, Pierre, Ménard, Robert, Mécheri, Salaheddine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986535/ https://www.ncbi.nlm.nih.gov/pubmed/27432939 http://dx.doi.org/10.1084/jem.20151976 |
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