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Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour
A central pathological hallmark of Parkinson's disease (PD) is the presence of proteinaceous depositions known as Lewy bodies, which consist largely of the protein α-synuclein (aSyn). Mutations, multiplications and polymorphisms in the gene encoding aSyn are associated with familial forms of PD...
Autores principales: | Breda, Carlo, Nugent, Marie L., Estranero, Jasper G., Kyriacou, Charalambos P., Outeiro, Tiago F., Steinert, Joern R., Giorgini, Flaviano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986550/ https://www.ncbi.nlm.nih.gov/pubmed/25305083 http://dx.doi.org/10.1093/hmg/ddu521 |
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