Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learned

An important pathogenetic distinction in the classification of myeloproliferative neoplasms (MPNs) is the presence or absence of the BCR–ABL fusion gene, which encodes a unique oncogenic tyrosine kinase. The BCR–ABL fusion, caused by the formation of the Philadelphia chromosome (Ph) through transloc...

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Detalles Bibliográficos
Autores principales: Pinilla-Ibarz, Javier, Sweet, Kendra L, Corrales-Yepez, Gabriela M, Komrokji, Rami S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986686/
https://www.ncbi.nlm.nih.gov/pubmed/27570458
http://dx.doi.org/10.2147/OTT.S102504

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