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Peripheral Blood Mitochondrial DNA Damage as a Potential Noninvasive Biomarker of Diabetic Retinopathy

PURPOSE: In the development of diabetic retinopathy, retinal mitochondria become dysfunctional, and mitochondrial DNA (mtDNA) is damaged. Because retinopathy is a progressive disease, and circulating glucose levels are high in diabetes, our aim was to investigate if peripheral blood mtDNA damage can...

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Detalles Bibliográficos
Autores principales: Mishra, Manish, Lillvis, John, Seyoum, Berhane, Kowluru, Renu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986770/
https://www.ncbi.nlm.nih.gov/pubmed/27494345
http://dx.doi.org/10.1167/iovs.16-19073