RANK and RANK ligand expression in primary human osteosarcoma

Receptor activator of nuclear factor kappa-B ligand (RANKL) is an essential mediator of osteoclast formation, function and survival. In patients with solid tumor metastasis to the bone, targeting the bone microenvironment by inhibition of RANKL using denosumab, a fully human monoclonal antibody (mAb...

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Detalles Bibliográficos
Autores principales: Branstetter, Daniel, Rohrbach, Kathy, Huang, Li-Ya, Soriano, Rosalia, Tometsko, Mark, Blake, Michelle, Jacob, Allison P., Dougall, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986823/
https://www.ncbi.nlm.nih.gov/pubmed/27556008
http://dx.doi.org/10.1016/j.jbo.2015.06.002

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