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Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs
The RNA exosome is a conserved complex for RNA degradation with two ribonucleolytic subunits, Dis3 and Rrp6. Rrp6 is a 3′–5′ exonuclease, but it also has a structural role in helping target RNAs to the Dis3 activity. The relative importance of the exonuclease activity and the targeting activity prob...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986887/ https://www.ncbi.nlm.nih.gov/pubmed/27402898 http://dx.doi.org/10.1261/rna.051490.115 |