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Evolving specificity of tRNA 3-methyl-cytidine-32 (m(3)C32) modification: a subset of tRNAs(Ser) requires N(6)-isopentenylation of A37

Post-transcriptional modifications of anticodon loop (ACL) nucleotides impact tRNA structure, affinity for the ribosome, and decoding activity, and these activities can be fine-tuned by interactions between nucleobases on either side of the anticodon. A recently discovered ACL modification circuit i...

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Detalles Bibliográficos
Autores principales: Arimbasseri, Aneeshkumar G., Iben, James, Wei, Fan-Yan, Rijal, Keshab, Tomizawa, Kazuhito, Hafner, Markus, Maraia, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986895/
https://www.ncbi.nlm.nih.gov/pubmed/27354703
http://dx.doi.org/10.1261/rna.056259.116