The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion

Stress adaptation plays a pivotal role in biological processes and requires tight regulation of gene expression. In this study, we explored the effect of cellular stress on mRNA polyadenylation and investigated the implications of regulated polyadenylation site usage on mammalian gene expression. Hi...

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Detalles Bibliográficos
Autores principales: Hollerer, Ina, Curk, Tomaz, Haase, Bettina, Benes, Vladimir, Hauer, Christian, Neu-Yilik, Gabriele, Bhuvanagiri, Madhuri, Hentze, Matthias W., Kulozik, Andreas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986898/
https://www.ncbi.nlm.nih.gov/pubmed/27407180
http://dx.doi.org/10.1261/rna.055657.115

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