Activation of Chymotrypsin-Like Activity of the Proteasome during Ischemia Induces Myocardial Dysfunction and Death

Inhibitors of the ubiquitin-proteasome system improve hemodynamic parameters and decrease the infarct size after ischemia reperfusion. The molecular basis of this protection is not fully understood since most available data report inhibition of the 26 proteasome after ischemia reperfusion. The decre...

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Detalles Bibliográficos
Autores principales: Sanchez, Gina, Berrios, Daniela, Olmedo, Ivonne, Pezoa, Javier, Riquelme, Jaime A., Montecinos, Luis, Pedrozo, Zully, Donoso, Paulina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986934/
https://www.ncbi.nlm.nih.gov/pubmed/27529620
http://dx.doi.org/10.1371/journal.pone.0161068

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