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The Course of Skin and Serum Biomarkers of Advanced Glycation Endproducts and Its Association with Oxidative Stress, Inflammation, Disease Severity, and Mortality during ICU Admission in Critically Ill Patients: Results from a Prospective Pilot Study
BACKGROUND: Advanced glycation end products (AGEs) have been implicated in multiple organ failure, predominantly via their cellular receptor (RAGE) in preclinical studies. Little is known about the time course and prognostic relevance of AGEs in critically ill human patients, including those with se...
Autores principales: | Meertens, John H., Nienhuis, Hans L., Lefrandt, Joop D., Schalkwijk, Casper G., Nyyssönen, Kristiina, Ligtenberg, Jack J. M., Smit, Andries J., Zijlstra, Jan G., Mulder, D. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986948/ https://www.ncbi.nlm.nih.gov/pubmed/27529340 http://dx.doi.org/10.1371/journal.pone.0160893 |
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