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Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules

Major histocompatibility complex class I (MHCI) glycoproteins present cytosolic peptides to CD8+ T cells and regulate NK cell activity. Their heavy chains (HC) are expressed from up to three MHC gene loci (human leukocyte antigen [HLA]-A, -B, and -C in humans), whose extensive polymorphism maps pred...

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Detalles Bibliográficos
Autores principales:	Prevosto, Claudia, Usmani, M. Farooq, McDonald, Sarah, Gumienny, Aleksandra M., Key, Tim, Goodman, Reyna S., Gaston, J. S. Hill, Deery, Michael J., Busch, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987023/ https://www.ncbi.nlm.nih.gov/pubmed/27529174 http://dx.doi.org/10.1371/journal.pone.0161011

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