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Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data

High resolution melting (HRM) is a simple and rapid method for screening mutations. It offers various advantages for clinical diagnostic applications. Conventional HRM analysis often yields equivocal results, especially for surgically obtained tissues. We attempted to improve HRM analyses for more e...

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Detalles Bibliográficos
Autores principales:	Hatae, Ryusuke, Hata, Nobuhiro, Yoshimoto, Koji, Kuga, Daisuke, Akagi, Yojiro, Murata, Hideki, Suzuki, Satoshi O., Mizoguchi, Masahiro, Iihara, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987040/ https://www.ncbi.nlm.nih.gov/pubmed/27529619 http://dx.doi.org/10.1371/journal.pone.0160489

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