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A New Method for Identifying Essential Proteins Based on Network Topology Properties and Protein Complexes

Essential proteins are indispensable to the viability and reproduction of an organism. The identification of essential proteins is necessary not only for understanding the molecular mechanisms of cellular life but also for disease diagnosis, medical treatments and drug design. Many computational met...

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Detalles Bibliográficos
Autores principales: Qin, Chao, Sun, Yongqi, Dong, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987049/
https://www.ncbi.nlm.nih.gov/pubmed/27529423
http://dx.doi.org/10.1371/journal.pone.0161042