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A New Method for Identifying Essential Proteins Based on Network Topology Properties and Protein Complexes
Essential proteins are indispensable to the viability and reproduction of an organism. The identification of essential proteins is necessary not only for understanding the molecular mechanisms of cellular life but also for disease diagnosis, medical treatments and drug design. Many computational met...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987049/ https://www.ncbi.nlm.nih.gov/pubmed/27529423 http://dx.doi.org/10.1371/journal.pone.0161042 |