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Small GTPases Rab8a and Rab11a Are Dispensable for Rhodopsin Transport in Mouse Photoreceptors

Rab11a and Rab8a are ubiquitous small GTPases shown as required for rhodopsin transport in Xenopus laevis and zebrafish photoreceptors by dominant negative (dn) disruption of function. Here, we generated retina-specific Rab11a ((ret)Rab11a) and Rab8a ((ret)Rab8a) single and double knockout mice to e...

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Detalles Bibliográficos
Autores principales: Ying, Guoxin, Gerstner, Cecilia D., Frederick, Jeanne M., Boye, Sanford L., Hauswirth, William W., Baehr, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987053/
https://www.ncbi.nlm.nih.gov/pubmed/27529348
http://dx.doi.org/10.1371/journal.pone.0161236