CpG Methylation Analysis of HPV16 in Laser Capture Microdissected Archival Tissue and Whole Tissue Sections from High Grade Anal Squamous Intraepithelial Lesions: A Potential Disease Biomarker

Incidence and mortality rates of anal cancer are increasing globally. More than 90% of anal squamous cell carcinomas (ASCC) are associated with human papillomavirus (HPV). Studies on HPV-related anogenital lesions have shown that patterns of methylation of viral and cellular DNA targets could potent...

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Detalles Bibliográficos
Autores principales: Molano, Monica, Tabrizi, Sepehr N., Garland, Suzanne M., Roberts, Jennifer M., Machalek, Dorothy A., Phillips, Samuel, Chandler, David, Hillman, Richard J., Grulich, Andrew E., Jin, Fengyi, Poynten, I. Mary, Templeton, David J., Cornall, Alyssa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987059/
https://www.ncbi.nlm.nih.gov/pubmed/27529629
http://dx.doi.org/10.1371/journal.pone.0160673

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