Cargando…
Mechanistic studies and radiofluorination of structurally diverse pharmaceuticals with spirocyclic iodonium(iii) ylides
Synthesis of non-activated electron-rich and sterically hindered (18)F-arenes remains a major challenge due to limitations of existing radiofluorination methodologies. Herein, we report on our mechanistic investigations of spirocyclic iodonium(iii) ylide precursors for arene radiofluorination, inclu...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987086/ https://www.ncbi.nlm.nih.gov/pubmed/27540460 http://dx.doi.org/10.1039/c6sc00197a |