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Enantiospecific Synthesis and Cytotoxicity Evaluation of Oximidine II Analogues

Analogues of the anticancer natural product oximidine II were prepared and evaluated for cytotoxicity. One analogue of oximidine II that carries a C15 allylic amide side chain as well as two analogues with C15 vinyl sulfone side chains were found to lack cytotoxicity against the cancer cell line SK‐...

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Detalles Bibliográficos
Autores principales: Schneider, Christopher M., Li, Wei, Khownium, Kriangsak, Lushington, Gerald H., Georg, Gunda I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987132/
https://www.ncbi.nlm.nih.gov/pubmed/27240557
http://dx.doi.org/10.1002/cmdc.201600024